Abstract. Western boundary currents act as transport pathways for nutrient-rich waters from low to high latitudes (nutrient streams) and are responsible for maintaining mid- and high-latitude productivity in the North Atlantic and North Pacific. This study investigates the centennial oxygen (O₂) and nutrient changes over the Northern Hemisphere in the context of the projected warming and general weakening of the Atlantic Meridional Overturning Circulation (AMOC) in a subset of Earth System Models included in the CMIP5 catalogue. In all models examined, the Atlantic warms faster than the Pacific Ocean, resulting in a greater basin-scale solubility decrease. However, this thermodynamic tendency is compensated by the changes in the biologically-driven O₂ consumption which dominates the overall O₂ budget. These changes are linked to the slow-down of the nutrient stream in this basin, in response to the AMOC weakening. The North Atlantic resists the warming-induced deoxygenation due to the weakened biological carbon export and remineralization, leading to higher O₂ levels. On the contrary, the projected nutrient stream and macro-nutrient inventory in the North Pacific remain nearly unchanged.