We present the first high-resolution (500 m × 500 m) gridded methane (CH<sub>4</sub>) emission inventory for Switzerland, which integrates the national emission totals reported to the United Nations Framework Convention on Climate Change (UNFCCC) and recent CH<sub>4</sub> flux studies conducted by research groups across Switzerland. In addition to anthropogenic emissions, we also include natural and semi-natural CH<sub>4</sub> fluxes, i.e., emissions from lakes and reservoirs, wetlands, wild animals as well as uptake by forest soils. National CH<sub>4</sub> emissions were disaggregated using detailed geostatistical information on source locations and their spatial extent and process- or area-specific emission factors. In Switzerland, the highest CH<sub>4</sub> emissions in 2011 originated from the agricultural sector (150 Gg CH<sub>4</sub> yr<sup>−1</sup>), mainly produced by ruminants and manure management, followed by emissions from waste management (15 Gg CH<sub>4</sub> yr<sup>−1</sup>) mainly from landfills and the energy sector (12 Gg CH<sub>4</sub> yr<sup>−1</sup>), which was dominated by emissions from natural gas distribution. Compared to the anthropogenic sources, emissions from natural and semi-natural sources were relatively small (6 Gg CH<sub>4</sub> yr<sup>−1</sup>), making up only 3 % of the total emissions in Switzerland. CH<sub>4</sub> fluxes from agricultural soils were estimated to be not significantly different from zero (between −1.5 and 0 Gg CH<sub>4</sub> yr<sup>−1</sup>), while forest soils are a CH<sub>4</sub> sink (approx. −2.8 Gg CH<sub>4</sub> yr<sup>−1</sup>), partially offsetting other natural emissions. Estimates of uncertainties are provided for the different sources, including an estimate of spatial disaggregation errors deduced from a comparison with a global (EDGAR v4.2) and a European CH<sub>4</sub> inventory (TNO/MACC). This new spatially-explicit emission inventory for Switzerland will provide valuable input for regional scale atmospheric modeling and inverse source estimation.